Jackie Syrop


Most Biologics Have Good Tolerability in Clinical Settings

September 28, 2017

A study by Cristina Scavone, MS, and colleagues, published in Frontiers in Pharmacology, concludes that most biologic drugs used to treat cancer, rheumatoid arthritis, and psoriatic arthritis in real-world clinical settings demonstrate overall good tolerability

Study Shows Patients With Ulcerative Colitis Prefer Adalimumab to Infliximab

September 27, 2017

A study of Japanese patients with ulcerative colitis who were naïve to anti–tumor necrosis factor treatment found that patients preferred adalimumab to infliximab, but the researchers also reported no differences in the efficacy of the 2 treatments.

Canadian Study Finds High Adherence to Anti-TNF Agents in Inflammatory Diseases

September 26, 2017

A large Canadian study of patients with inflammatory diseases, including rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, reports that a high overall rate of adherence to subcutaneous anti-TNFs.

CT-P10 Shows Comparable Efficacy to Rituxan in Network Meta-Analysis

September 25, 2017

The rituximab biosimilar CT-P10 (Celltrion and Teva’s Truxima), which is approved in the European Union and under review by the FDA in the United States, showed comparable effectiveness to reference rituximab (Genentech and Biogen’s innovator product, sold as Mabthera and Rituxan) in a network meta-analysis.

Considerations for Switching Biologics in the Treatment of Psoriatic Arthritis

September 20, 2017

When a patient fails to respond or no longer responds to one biologic disease-modifying antirheumatic drug due to a lack of efficacy or poor tolerability, switching to another bDMARD can be a safe and effective treatment strategy.

Drug Modulation Can Resolve Low-Level Anti-TNF Drug Antibodies in IBD

September 19, 2017

A retrospective case series suggests that low-level anti-tumor necrosis factor anti-drug antibodies in patients with inflammatory bowel disease may be overcome by dose escalation and/or addition of an immunomodulator, which can allow for clinical improvement in disease status.