Deana Ferreri, PhD


Patients With IBD Experience Nocebo Effect Post Mandatory Switch to Biosimilar

May 11, 2024

In Canada, a study on inflammatory bowel disease (IBD) patients switching to infliximab or adalimumab biosimilars found no change in clinical remission or antidrug antibodies after 24 weeks, but 13% experienced the nocebo effect, leading to one-fifth discontinuing biosimilar therapy.

Review: Product Attributes Relevant to Injection-Site Pain, Adalimumab Treatment

May 04, 2024

A review article summarizes the product attributes of reference and biosimilar adalimumab products, such as formulation with or without citrate, delivery volume, and needle gauge, relevant to patients’ experience of injection-site pain.

Patient Perceptions of Switching From the Reference Adalimumab to Amjevita During Its Initial Launch

April 20, 2024

In a survey of patients with autoimmune arthritis who had been switched from reference adalimumab (Humira) to biosimilar adalimumab-atto (Amjevita; Amgen), most reported preferring the biosimilar and had no concerns about switching.

What Clinicians Need to Know About Using Biosimilars to Treat IBD

April 13, 2024

A review article, intended to act as a guide for clinicians, summarizes the available infliximab and adalimumab biosimilars for treating inflammatory bowel disease (IBD) as well as others that are coming down the pipeline.

Meta-Analysis Confirms Similar Safety, Efficacy Between Adalimumab Biosimilars, Humira

April 06, 2024

A systematic review and meta-analysis of 7 randomized controlled trials found no significant differences in efficacy and safety indicators between adalimumab biosimilars and the reference product (Humira) for treatment of moderate to severe psoriasis.

Physician and Patient Perspectives After Starting or Switching to Amgevita in IBD

March 23, 2024

A real-world study surveying physicians and patients on adalimumab biosimilar ABP 501 (Amgevita) in inflammatory bowel disease (IBD) found both patients initiating ABP 501 and those who had switched from the reference product had higher satisfaction levels.