Allison Inserro


Fewer Than One-Third of New Patients With RA Receive Disease-Modifying Medications, Study Says

August 20, 2019

Fewer than one-third of patients newly diagnosed with rheumatoid arthritis (RA) used anti–tumor necrosis factors agents, other biologics, Janus kinase inhibitors, or conventional disease-modifying antirheumatic drugs in 2014.

Study of Denmark's Mandatory Etanercept Switch Finds No Obvious Changes in Healthcare Utilization, Costs

August 19, 2019

Researchers examining the mandatory switch of patients with rheumatoid arthritis (RA) from the originator etanercept (Enbrel) to the biosimilar etanercept (Benepali) found no changes in overall healthcare utilization or cost of healthcare following the switch.

GAO Report on Medicare Part D Finds PBMs Earned Little Revenue From Spread Pricing

August 16, 2019

With rising concern over rising drug prices, policymakers have sought a better understanding of the roles of pharmacy benefit managers (PBMs) in the drug supply chain and plans' and PBMs' efforts to manage Part D drug spending and use.

Point-of-Care Test Nearly Identical to ELISA at Detecting ADAs to Biosimilar Infliximab, SB2

August 15, 2019

A recent study of a rapid point-of-care (POC) test shows that it is virtually identical at detecting antidrug antibodies (ADAs) to a biosimilar infliximab, SB2 (Renflexis, Flixabi), as a standard enzyme-linked immunosorbent assay (ELISA) and is suitable for therapeutic drug monitoring of any infliximab product.

Change Dosing Regimens To Lower Drug Costs? It's Possible, Researchers Say

August 09, 2019

The August issue of JAMA Oncology features a Viewpoint that puts forth a free-market solution to lower high drug costs by changing dosing regimens without hurting efficacy using the approach of interventional pharmacoeconomics (IVPE).

UK Group Reports on a Successful Switch to Biosimilar Etanercept

August 07, 2019

Anti–tumor necrosis factor medicines are one of the costliest drugs for many health systems, and in the United Kingdom, a recent article described how one clinical commissioning group managed the switch of patients on the originator etanercept (Enbrel) to a biosimilar (Benepali) using a fixed-price model.

Debate Over Whether Biologics Constitute Natural Monopolies Continues

August 01, 2019

“We wish biosimilar competition would efficiently lower biologics prices to the socially optimal level of marginal economic cost,” wrote Bach and coauthors. “But, in this case, the ideological preference for competition needs to be put aside for a more effective, efficient, and economically justified approach of regulating biologics as natural monopolies.”